Potency vs Cleanliness in GHRPs

Every GHRP agonizes the ghrelin receptor, but they differ in how cleanly they do it. GHRP-2 produces a stronger GH pulse than GHRP-6, which makes it attractive for body-composition research. The cost is more off-target activity: appetite stimulation is real, and cortisol and prolactin can rise at higher doses.

Ipamorelin sits at the opposite end — less potent but far cleaner. Members weigh this constantly: do you want the bigger pulse (GHRP-2) or the tolerable side-effect profile (ipamorelin)? The discussion below captures both camps.