DAC vs No-DAC: Convenience vs Physiology

The DAC linker is the entire story of this compound. By binding albumin, it stretches CJC-1295's half-life from ~30 minutes to roughly a week — a remarkable engineering feat that allows once- or twice-weekly dosing.

But the same property that makes it convenient also flattens the GH curve. Native growth hormone is released in discrete pulses; a week-long signal produces a steadier elevation that, while effective for raising IGF-1, is less physiological. Members who prioritize mimicking natural rhythm tend to prefer the no-DAC variant dosed more frequently; those who prioritize adherence favor DAC. There is no universally correct answer, and the thread below is where members hash it out.