GHRH + GHRP Synergy

Growth hormone release is controlled by two signals: GHRH (which says 'release GH') and ghrelin (which amplifies that signal). CJC-1295 + Ipamorelin engages both, which is why the combination is the canonical GH-secretagogue stack.

The synergy is well-established in physiology — both pathways converge on the pituitary. Members discuss this blend as one of the more mechanistically justified combinations in peptide research.